Hearing loss in Vogt-Koyanagi-Harada syndrome: case report and literature review
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Abstract
Vogt-Koyanagi-Harada syndrome (VKHS) is a rare multisystemic granulomatous disease, characterized by severe bilateral panuveitis and serous retinal detachment; it can be associated with a wide spectrum of extraocular symptoms, such as auditory symptoms, and the most common condition is sensorineural hearing loss. Its etiology is recognized as a T-cell-mediated autoimmune response against melanocyte antigens present in the choroid, meninges, cochlea, and skin. Likewise, host genetic factors have been identified as predisposing for its development, specifically the presence of the HLA-DR4 allele, the HLA-DRB1 0405 subtype is the most studied up to date. Treatment is based on the administration of high doses of systemic corticosteroids, however, there is not much evidence that specifically evaluates the efficacy of these medications on their audiovestibular manifestations. This article presents a clinical case of VKH syndrome with concomitant hearing impairment and carries out a short narrative review of the literature.
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ISSN: 0120-8411
References
Greco A, Fusconi M, Gallo A, Turchetta R, Marinelli C, Macri GF, et al. Vogt-Koyanagi-Harada syndrome. Autoimmun Rev. 2013;12(11):1033-8. doi: 10.1016/j.autrev.2013.01.004
O’Keefe GA, Rao NA. Vogt-Koyanagi-Harada disease. Surv Ophthalmol. 2017;62(1):1-25. doi: 10.1016/j. survophthal.2016.05.002
Sakata VM, da Silva FT, Hirata CE, de Carvalho JF, Yamamoto JH. Diagnosis and classification of Vogt-Koyanagi-Harada disease. Autoimmun Rev. 2014;13(4-5):550-5. doi: 10.1016/j. autrev.2014.01.023
Lavezzo MM, Sakata VM, Morita C, Rodriguez EE, Abdallah SF, da Silva FT, et al. Vogt-Koyanagi-Harada disease: review of a rare autoimmune disease targeting antigens of melanocytes. Orphanet J Rare Dis. 2016;11:29. doi: 10.1186/s13023-016-0412-4
Mota L, Santos A. Síndrome de Vogt-Koyanagi-Harada e o seu acometimento multissistêmico. Rev. Assoc. Med. Bras. 2010;56(5):590-95. doi: 10.1590/S0104-42302010000500023
Radic B, Vukojevic N, Petelin Gadze Z, Dapic Ivancic B, Barun B. Vogt-Koyanagi-Harada syndrome: importance of early treatment. Acta Neurol Belg. 2020;120(5):1217-19. doi: 10.1007/s13760-020-01273-x
Noguchi Y, Nishio A, Takase H, Miyanaga M, Takahashi H, Mochizuki M, et al. Audiovestibular findings in patients with Vogt-Koyanagi-Harada disease. Acta Otolaryngol. 2014;134(4):339-44. doi: 10.3109/00016489.2013.868604
Al Dousary S. Auditory and vestibular manifestations of Vogt Koyanagi-Harada disease. J Laryngol Otol. 2011;125(2):138- 41. doi: 10.1017/S0022215110001817
Chan EW, Sanjay S, Chang BC. Headache, red eyes, blurred vision and hearing loss. Diagnosis: Vogt-Koyanagi-Harada syndrome. CMAJ. 2010;182(11):1205-9. doi: 10.1503/cmaj.082069
Standardization of Uveitis Nomenclature (SUN) Working Group. Classification Criteria for Vogt-Koyanagi-Harada Disease. Am J Ophthalmol. 2021;228:205-11. doi: 10.1016/j.ajo.2021.03.036
Campos WR, Cenachi SPF, Soares MS, Gonçalves PF, Vasconcelos-Santos DV. Vogt-Koyanagi-Harada-like Disease following Yellow Fever Vaccination. Ocul Immunol Inflamm. 2021;29(1):124-27. doi: 10.1080/09273948.2019.1661498
Papasavvas I, Herbort CP Jr. Reactivation of Vogt-Koyanagi Harada disease under control for more than 6years, following anti-SARS-CoV-2 vaccination. J Ophthalmic Inflamm Infect. 2021;11(1):21. doi: 10.1186/s12348-021-00251-5
Ferreira MC, Matos IL, Mondelli MFCG. Audiological findings in the Vogt-Koyanagi-Harada Syndrome. Codas. 2020;32(5):e20190183. Portuguese, English. doi: 10.1590/2317-1782/20202019183
Rodríguez Rivera V, Garrigues H, Pinazo R. Evolución de la hipoacusia neurosensorial bilateral en el síndrome de Vogt Koyanagi Harada. Acta Otorrinolaringol Esp. 2011;62(6):465- 68. doi: 10.1016/j.otorri.2010.09.002
Pelosi S, Chandrasekhar SS. Intratympanic steroid use for hearing salvage in Vogt-Koyanagi-Harada syndrome. Ear Nose Throat J. 2011;90(12):574-7. doi: 10.1177/014556131109001206
Shivaram S, Nagappa M, Seshagiri DV, Shanthakumar JS, Panda SS, Anadure R, et al. Vogt-Koyanagi-Harada Syndrome - A Neurologist’s Perspective. Ann Indian Acad Neurol. 2021;24(3):405-9. doi: 10.4103/aian.AIAN_405_20
Lai TY, Chan RP, Chan CK, Lam DS. Effects of the duration of initial oral corticosteroid treatment on the recurrence of inflammation in Vogt-Koyanagi-Harada disease. Eye (Lond). 2009;23(3):543-8. doi: 10.1038/eye.2008.89
Diallo K, Revuz S, Clavel-Refregiers G, Sené T, Titah C, Gerfaud-Valentin M, et al. Vogt-Koyanagi-Harada disease: a retrospective and multicentric study of 41 patients. BMC Ophthalmol. 2020;20(1):395. doi: 10.1186/s12886-020-01656-x
AlHelali N, Hajr E, Almuhawas F, Hagr A. Bilateral Cochlear Implantation in Vogt-Koyanagi-Harada Syndrome: A Case Report. Otol Neurotol. 2019;40(7):e694-97. doi: 10.1097/ MAO.0000000000002262
Sydlowski SA, Luffler C, Haberkamp T. Successful cochlear implantation in a case of Vogt-Koyanagi-Harada disease. Otol Neurotol. 2014;35(9):1522-4. doi: 10.1097/ MAO.0000000000000353
Morita S, Nakamaru Y, Obara N, Masuya M, Fukuda S. Characteristics and prognosis of hearing loss associated with Vogt-Koyanagi-Harada disease. Audiol Neurootol. 2014;19(1):49-56. doi: 10.1159/000356386
Ondrey FG, Moldestad E, Mastroianni MA, Pikus A, Sklare D, Vernon E, et al. Sensorineural hearing loss in Vogt-Koyanagi Harada syndrome. Laryngoscope. 2006;116(10):1873-6. doi: 10.1097/01.mlg.0000234946.31603.fe