Prevalence of pediatric postintubation subglottic stenosis in a third level hospital in Colombia between 2017 and 2020

Main Article Content

Manuela Hurtado Gonzalez
Erika Sanchez Villegas
Juan Fernando Muñoz Tamayo
Julian Andres Sierra Jaramillo
Damian Martínez Soto

Abstract

Introduction: Pediatric orotracheal intubation has increased survival rates in severe illnesses; however, one of the consequences maybe the development of subglottic stenosis. This population is at a higher risk of developing it due to anatomical differences compared to adults. The incidence of subglottic stenosis following orotracheal intubation has decreased over time as reported in the literature. This study aimed to assess the prevalence of this condition in our population and describe the clinical, demographic, and diagnostic characteristics in the pediatric population diagnosed with subglottic stenosis following orotracheal intubation at the San Vicente Fundación Hospital. Additionally, it aimed to evaluate the prevalence of this diagnosis during the mentioned period. Materials and Methods: A retrospective study was conducted by reviewing medical records of patients with ICD-10 codes for laryngeal stenosis and for subglottic stenosis secondary to procedures. Also, the patients with the procedure code for orotracheal intubation were identified. A descriptive analysis was performed based on the distribution of variables. Results: The prevalence of subglottic stenosis was 13%. There was a majority of male cases, and the primary cause of intubation was lower respiratory tract infection, mainly bronchiolitis. The most frequent comorbidities included prematurity, swallowing disorders, and broncho-obstructive syndrome. Median duration of intubation was 19 days, and lower-grade stenosis was more commonly encountered. Conclusions: Subglottic stenosis is a complication of pediatric orotracheal intubation, with a prevalence of 13% in this study. Patients who develop this condition require one or more procedures to establish a patent airway and often experience prolonged hospital stays.

Downloads

Download data is not yet available.

Article Details

How to Cite
1.
Hurtado Gonzalez M, Sanchez Villegas E, Muñoz Tamayo JF, Sierra Jaramillo JA, Martínez Soto D. Prevalence of pediatric postintubation subglottic stenosis in a third level hospital in Colombia between 2017 and 2020. Acta otorrinolaringol cir cabeza cuello [Internet]. 2023Oct.24 [cited 2024Nov.23];51(3):205 - 211. Available from: https://revista.acorl.org.co/index.php/acorl/article/view/736
Section
Trabajos Originales

References

Farias JA, Frutos F, Esteban A, Flores JC, Retta A, Baltodano A, et al. What is the daily practice of mechanical ventilation in pediatric intensive care units? A multicenter study. Intensive Care Med. 2004;30(5):918-25. doi: 10.1007/s00134-004- 2225-5

Schweiger C, Manica D, Kuhl G, Sekine L, Marostica PJ. Post-intubation acute laryngeal injuries in infants and children: A new classification system. Int J Pediatr Otorhinolaryngol. 2016;86:177-82. doi: 10.1016/j.ijporl.2016.04.032

Marshak G, Grundfast KM. Subglottic stenosis. Pediatr Clin North Am. 1981;28(4):941-8. doi: 10.1016/S0031- 3955(16)34078-0

Monnier P. Pediatric Airway Surgery Management of Laryngotracheal Stenosis in Infants and Children. Berlín: Springer-Verlag Berlin Heidelberg; 2011.

Jefferson ND, Cohen AP, Rutter MJ. Subglottic stenosis. Semin Pediatr Surg. 2016;25(3):138-43. doi: 10.1053/j. sempedsurg.2016.02.006

Schweiger C, Marostica PJ, Smith MM, Manica D, Carvalho PR, Kuhl G. Incidence of post-intubation subglottic stenosis in children: prospective study. J Laryngol Otol. 2013;127(4):399- 403. doi: 10.1017/S002221511300025X

Jorgensen J, Wei JL, Sykes KJ, Klem SA, Weatherly RA, Bruegger DE, et al. Incidence of and risk factors for airway complications following endotracheal intubation for bronchiolitis. Otolaryngol Head Neck Surg. 2007;137(3):394- 9. doi: 10.1016/j.otohns.2007.03.041

Lezcano López AI. Resultados del tratamiento de estenosis subglótica en niños en la Fundación Hospital de la Misericordia entre los años 2009 a 2017 [Internet] [Tesis]. Bogotá: Universidad Nacional de Colombia; 2018 [citado el falta la fecha]. Disponible en: https://acortar.link/tem9yy

Schweiger C, Manica D, Pereira DRR, Carvalho PRA, Piva JP, Kuhl G, et al. Subsedação é um fato de risco para o desenvolvimento de estenose subglótica em crianças intubadas. J Pediatr (Rio J). 2017;93(4):351-5. doi: 10.1016/j. jped.2016.10.006

Lanari M, Prinelli F, Adorni F, Di Santo S, Vandini S, Silvestri M, et al. Risk factors for bronchiolitis hospitalization during the first year of life in a multicenter Italian birth cohort. Ital J Pediatr. 2015;41:40. doi: 10.1186/s13052-015-0149-z

Nagayama Y, Tsubaki T, Nakayama S, Sawada K, Taguchi K, Tateno N, et al. Gender analysis in acute bronchiolitis due to respiratory syncytial virus. Pediatr Allergy Immunol. 2006;17(1):29-36. doi: 10.1111/j.1399-3038.2005.00339.x

Schweiger C, Eneas LV, Manica D, Netto CSS, Carvalho PRA, Piva JP, et al. Accuracy of stridor-based diagnosis of post intubation subglottic stenosis in pediatric patients. J Pediatr (Rio J). 2020 Jan-Feb;96(1):39-45. doi: 10.1016/j.jped.2018.08.004

Cakir E, Atabek AA, Calim OF, Uzuner S, AlShadfan L, Yazan H, et al. Post-intubation subglottic stenosis in children: Analysis of clinical features and risk factors. Pediatr Int. 2020;62(3):386- 89. doi: 10.1111/ped.14122

Pinzas LA, Bedwell JR, Ongkasuwan J. Glottic and Subglottic Injury and Development of Pediatric Airway Stenosis. Otolaryngol Head Neck Surg. 2023;168(3):469-77. doi: 10.1177/01945998221100829

Debs S, Kazi AA, Bastaich D, Thacker L, Petersson RS. Prognostic factors in the management of pediatric subglottic stenosis. Int J Pediatr Otorhinolaryngol. 2021;151:110931. doi: 10.1016/j.ijporl.2021.110931

Lambercy K, Pincet L, Sandu K. Intubation Related Laryngeal Injuries in Pediatric Population. Front Pediatr. 2021;9:594832. doi: 10.3389/fped.2021.594832

Sherman JM, Lowitt S, Stephenson C, Ironson G. Factors influencing acquired subgottic stenosis in infants. J Pediatr. 1986;109(2):322-7. doi: 10.1016/s0022-3476(86)80395-x

Manica D, Schweiger C, Maróstica PJ, Kuhl G, Carvalho PR. Association between length of intubation and subglottic stenosis in children. Laryngoscope. 2013;123(4):1049-54. doi: 10.1002/lary.23771

Marston AP, White DR. Subglottic Stenosis. Clin Perinatol. 2018;45(4):787-804. doi: 10.1016/j.clp.2018.07.013

Arianpour K, Forman SN, Karabon P, Thottam PJ. Pediatric acquired subglottic stenosis: Associated costs and comorbidities of 7,981 hospitalizations. Int J Pediatr Otorhinolaryngol. 2019;117:51-56. doi: 10.1016/j.ijporl.2018.11.016

Most read articles by the same author(s)