Clinical characterization of invasive fungal rhinosinusitis in patients undergoing functional endoscopic surgery.
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Abstract
Introduction: Invasive fungal rhinosinusitis is an invasion of fungal microorganisms at the sinonasal level, which can extend to orbital and intracranial structures. It has a predilection for immunocompromised patients, being a cause of mortality in this population, which requires aggressive medical-surgical management. Objective: Identify the clinical characteristics of patients with invasive fungal rhinosinusitis due to mucormycosis who underwent functional endoscopic surgery. Methods: Retrospective cross-sectional study of patients from the Otorhinolaryngology Service with invasive fungal rhinosinusitis due to mucormycosis who underwent functional endoscopic surgery between January 1, 2015 and January 1, 2023 at the 20 de Noviembre National Medical Center in Mexico City. Results: A total of 16 patients with a diagnosis of invasive fungal rhinosinusitis were included, 7 women (43.75%) and 9 men (56.25%). The average age was 47 years; 68.75% had diabetes mellitus, 43.75% had arterial hypertension and 18.75% had acute lymphocytic leukemia. There were no surgical complications. Three patients (18.75%) presented prolonged neutropenia, 5 (31.25%) underwent enucleation and there was only one death. Conclusion: In patients with invasive fungal rhinosinusitis diagnosed with mucormycosis, the most common symptom was headache followed by nasal obstruction. The most common comorbidity was diabetes mellitus. Vascular disease, pneumonia and SARS-CoV-2 infection are statistically significantly associated with prolonged neutropenia.
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ISSN: 0120-8411
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