Characteristics of smell and taste alteration in patients with COVID-19

Main Article Content

María Manuela Chemás-Vélez
Nicolás Núñez-Ordoñez
Paula Andrea Téllez

Abstract

Introduction: Identifying symptoms or symptom combinations with a high predic­tive value for diagnosing a disease is a crucial strategy for controlling transmissible diseases. Smell and taste alterations have been identified as highly prevalent symp­toms of COVID-19 and have been used as a reliable early predictor of the disease. The objective in this study was characterizing the prevalence of smell and taste alterations in patients with COVID-19 in the Colombian population. Materials and methods: Cross-sectional, descriptive study. A telephonic and electronic survey was applied to adult patients with SARS-CoV-2 infection confirmed by PCR. Results: 182 patients were included. 59% presented with smell alterations and 54% with taste symptoms. Among these patients, 77% and 82% respectively perceived symp­tomatic improvement. 14% of patients presented smell alterations before the onset of other COVID-19 symptoms. 9% reported smell alterations to be the only symp­tom of the disease. 8% of patients perceived taste alterations as a first symptom and 6% reported it to be the only symptom of the disease. Conclusion: Taste and smell alterations are highly prevalent symptoms in Colombian patients with Covid-19 and in some cases they can be the either the first or the only perceived symptoms of the disease

Downloads

Download data is not yet available.

Article Details

How to Cite
1.
Chemás-Vélez MM, Núñez-Ordoñez N, Téllez PA. Characteristics of smell and taste alteration in patients with COVID-19. Acta otorrinolaringol cir cabeza cuello [Internet]. 2022Sep.30 [cited 2024Jul.3];50(3):195 - 200. Available from: https://revista.acorl.org.co/index.php/acorl/article/view/639
Section
Trabajos Originales

References

Coronavirus (COVID-19) Cases - Statistics and Research -Our World in Data [Internet]. [Citado el 08 de mayo de 2021].

Disponible en: https://ourworldindata.org/covid-cases

Lechien JR, Chiesa-Estomba CM, de Siati DR, Horoi M, le Bon SD, Rodriguez A, et al. Olfactory and gustatory dysfunctions

as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European

study. Eur Arch Otorhinolaryngol. 2020;277(8):2251-61. doi:10.1007/s00405-020-05965-1.

Menni C, Valdes AM, Freidin MB, Ganesh S, El-Sayed Moustafa JS, Visconti A, et al. Loss of smell and taste in

combination with other symptoms is a strong predictor of COVID-19 infection. medRxiv. 2020.04.05.20048421. doi:

1101/2020.04.05.20048421.

Tong JY, Wong A, Zhu D, Fastenberg JH, Tham T. The prevalence of olfactory and gustatory dysfunction in COVID-19 patients: a systematic review and meta-analysis. Otolaryngol Head Neck Surg. 2020;163(1):3-11. doi: 10.1177/0194599820926473.

Yan CH, Faraji F, Prajapati DP, Boone CE, DeConde AS. Association of chemosensory dysfunction and COVID-19 in

patients presenting with influenza-like symptoms. Int Forum Allergy Rhinol. 2020;10(7):806-13. doi: 10.1002/alr.22579.

Hjelmesæth J, Skaare D. Loss of smell or taste as the only symptom of COVID-19. Tidsskr Nor Laegeforen. 2020;140(7).

doi: 10.4045/tidsskr.20.0287.

Vroegop AV, Eeckels AS, Van Rompaey V, Abeele D, Schiappoli MS, Alobid I, et al. COVID-19 and olfactory dysfunction - an

ENT perspective to the current COVID-19 pandemic. B-Ent. 2020;16(1):81-5. doi: 10.5152/B-ENT.2020.20127.

Vargas-Gandica J, Winter D, Schnippe R, Rodríguez-Morales AG, Mondragon J, Escalera-Antezana JP, et al. Ageusia and

anosmia, a common sign of COVID-19? A case series from four countries. J Neurovirol. 2020;26(5):785-9. doi: 10.1007/

s13365-020-00875-8.

National Health and Nutrition Examination Survey 2013-2014 data documentation, codebook, and frequencies taste & smell (CSQ_H).

Boesveldt S, Postma EM, Boak D, Welge-Luessen A, Schöpf V, Mainland JD, et al. Anosmia-A clinical review. Chem Senses. 2017;42(7):513-23. doi: 10.1093/chemse/bjx025.

Young BE, Ong SWX, Kalimuddin S, Low JG, Tan SY, Loh J, et al. Epidemiologic features and clinical course of

patients infected with SARS-CoV-2 in Singapore. JAMA.2020;323(15):1488-94. doi: 10.1001/jama.2020.3204.

Marchese-Ragona R, Ottaviano G, Piero N, Vianello A, Miryam C. Sudden hyposmia as a prevalent symptom of COVID-19

infection. medRxiv. 2020. doi: 10.1101/2020.04.06.20045393.

Sungnak W, Huang N, Bécavin C, Berg M; HCA Lung Biological Network. SARS-CoV-2 entry genes are most highly

expressed in nasal goblet and ciliated cells within human airways. ArXiv. 2020:arXiv:2003.06122v1. Update in: Nat

Med. 2020;26(5):681-7.

Kalinke U, Bechmann I, Detje CN. Host strategies against virus entry via the olfactory system. Virulence. 2011;2(4):367-70.doi: 10.4161/viru.2.4.16138.

Brann DH, Tsukahara T, Weinreb C, Lipovsek M, Van den Berge K, Gong B, et al. Non-neuronal expression of

SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia. Sci Adv. 2020;6(31):eabc5801. doi: 10.1126/sciadv.abc5801.

Addison AB, Wong B, Ahmed T, Macchi A, Konstantinidis I, Huart C, et al. Clinical Olfactory Working Group consensus

statement on the treatment of postinfectious olfactory dysfunction. J Allergy Clin Immunol. 2021;147(5):1704-1719.

doi: 10.1016/j.jaci.2020.12.641.

Abdelalim AA, Mohamady AA, Elsayed RA, Elawady MA, Ghallab AF. Corticosteroid nasal spray for recovery of smell

sensation in COVID-19 patients: A randomized controlled trial. Am J Otolaryngol. 2021;42(2):102884. doi: 10.1016/j.

amjoto.2020.102884.

Hummel T, Reden KRJ, Hähner A, Weidenbecher M, Hüttenbrink KB. Effects of olfactory Training in patients with

olfactory loss. Laryngoscope. 2009;119(3):496-9. doi: 10.1002/lary.20101.

Altundag A, Cayonu M, Kayabasoglu G, Salihoglu M, Tekeli H, Saglam O, et al. Modified olfactory training in patients with postinfectious olfactory loss. Laryngoscope. 2015;125(8):1763-6. doi: 10.1002/lary.25245.

Henning H. Der Geruch. johann ambrosius barth verlag. 1916.