Treatment of tinnitus with sound stimulator with frequency specificity
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Abstract
Introduction: tinnitus can affect the quality of life of a patient. Acoustic stimulation can be used as treatment when the cause of tinnitus is located in the cochlea.
Objective: Determine change in tinnitus perception before and after therapeutic intervention.
Methodology: We performed a case series study. Patients with non-pulsatile tinnitus, with no improvement with medical therapy, and grade moderate- catastrophic were treated with the REVE 134™ system. A microaudiometry (67 frequencies) was performed to determine the cochlear regions affected. Patients with auditory thresholds >60 dB, retrocochlear pathologies, and who did not want to participate in the study were excluded. The variables studied were THI (“Tinnitus Handicap Inventory”), VAS (Visual Analog Scale) and TQR (“Tinnitus Reaction Questionnaire”), that were measured before, three, and six months after treatment.
Results: 11 patients (male: 5, women: 6) were included. In 5 of them tinnitus was bilateral, and in 6 unilateral. Pretreatment values were: THI=61.4±27.4, VAS=6.9±2.7 and TQR=43.2±31.9 (Kolmogorov-Smirnov, p>0.05). We found improvement in tinnitus perception with the therapy, and this values had statistical significance (THI (3mo=30.6±21.1; 6mo=19±19.2), VAS (3mo=5.6±2.3; 6mo=3.5±2.0), TQR (3mo=25.6±20.0; 6mo=14.3±19.9); repetitive measures of ANOVA (p=0.007, p=0.027, p=0.037; respectively)).
Conclusion: Treatment with REVE 134™ was effective in patients with moderate to catastrophic tinnitus.
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Este artículo es publicado por la Revista Acta de Otorrinolaringología & Cirugía de Cabeza y Cuello.
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eISSN: 2539-0856
ISSN: 0120-8411
References
Longenecker RJ, Galazyuk AV. Methodological optimization of tinnitus assessment using prepulse inhibition of the acoustic startle reflex. Brain Res. 2012;1485:54-62. doi: 10.1016/j.brainres.2012.02.067
Shargorodsky J, Curhan SG, Curhan GC, Eavey R. Change in prevalence of hearing loss in US adolescents. JAMA. 2010;304(7):772-8. doi: 10.1001/jama.2010.1124
Noreña AJ, Eggermont JJ. Enriched acoustic environment after noise trauma reduces hearing loss and prevents cortical map reorganization. J Neurosci. 2005;25(3):699-705. doi: 10.1523/JNEUROSCI.2226-04.2005
Noreña AJ, Eggermont JJ. Changes in spontaneous neural activity immediately after an acoustic trauma: implications for neural correlates of tinnitus. Hear Res. 2003;183(1-2):137-53. doi: 10.1016/s0378-5955(03)00225-9
Calford MB. Dynamic representational plasticity in sensory cortex. Neuroscience. 2002;111(4):709-38. doi: 10.1016/s0306-4522(02)00022-2
Noreña AJ, Tomita M, Eggermont JJ. Neural changes in cat auditory cortex after a transient pure-tone trauma. J Neurophysiol. 2003;90(4):2387-401. doi: 10.1152/jn.00139.2003
Norena A, Micheyl C, Chéry-Croze S, Collet L. Psychoacoustic characterization of the tinnitus spectrum: implications for the underlying mechanisms of tinnitus. Audiol Neurootol. 2002;7(6):358-69. doi: 10.1159/000066156
Willott JF. Effects of sex, gonadal hormones, and augmented acoustic environments on sensorineural hearing loss and the central auditory system: insights from research on C57BL/6J mice. Hear Res. 2009;252(1-2):89-99. doi: 10.1016/j.heares.2008.12.002
Kwak E, Kwak S, Song S, Kim S, Hong S. A new method for restoration of sensorineural hearing loss: a prospective clinical study. Seúl: Samsung Medical Center; 2012
Disponible en: https://biosom.com.br/restoration_of_hearing_loss.pdf
Baguley DM, Andersson G. Factor analysis of the Tinnitus Handicap Inventory. Am J Audiol. 2003;12(1):31-4. doi: 10.1044/1059-0889(2003/007)
Nondahl DM, Cruickshanks KJ, Huang GH, Klein BE, Klein R, Nieto FJ, et al. Tinnitus and its risk factors in the Beaver Dam offspring study. Int J Audiol. 2011;50(5):313-20. doi: 10.3109/14992027.2010.551220
Tyler RS, Baker LJ. Difficulties experienced by tinnitus sufferers. J Speech Hear Disord. 1983;48(2):150-4. doi: 10.1044/jshd.4802.150
Tunkel DE, Bauer CA, Sun GH, Rosenfeld RM, Chandrasekhar SS, Cunningham ER Jr, et al. Clinical practice guideline: tinnitus. Otolaryngol Head Neck Surg. 2014;151(2 Suppl):S1-S40. doi: 10.1177/0194599814545325
Auerbach BD, Rodrigues PV, Salvi RJ. Central gain control in tinnitus and hyperacusis. Front Neurol. 2014;5:206. doi: 10.3389/fneur.2014.00206
Willott JF, Bosch JV, Shimizu T, Ding DL. Effects of exposing DBA/2J mice to a high-frequency augmented acoustic environment on the cochlea and anteroventral cochlear nucleus. Hear Res. 2006;216-217:138-45. doi: 10.1016/j.heares.2006.01.010
Willott JF, Turner JG, Sundin VS. Effects of exposure to an augmented acoustic environment on auditory function in mice: roles of hearing loss and age during treatment. Hear Res. 2000;142(1-2):79-88. doi: 10.1016/s0378-5955(00)00014-9