Nasal ala Alveolar Rhabdomyosarcoma in a pediatric patient. A rare case report

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María Paula Olivera-Arenas
Luis Felipe Romero-Moreno
Gilberto Eduardo Marrugo-Pardo
Julián Tavera-Cordero

Abstract

Given preferential nasal breathing in the first months of life in the pediatric population, nasal obstruction has more clinical repercussions than it would have in adults, hence the need to give higher priority to its diagnosis and management. One of the main causes of nasal obstruction in children is the presence of nasal masses, which cause considerable diagnostic uncertainty in the medical team, because of their multiple etiologies. In this article, the case of a 10-month-old patient with a rapidly growing mass in the nasal ala is presented. A rhabdomyosarcoma was promptly diagnosed and adequately managed. Rhabdomyosarcoma with an alveolar pattern occurs in an unusual way in this location; for this reason, this case is important in order to include this possibility in the diagnostic algorithm and, as was the case in this patient, reach an early diagnosis and institute adequate treatment resulting in favorable aesthetic and functional results.

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How to Cite
1.
Olivera-Arenas MP, Romero-Moreno LF, Marrugo-Pardo GE, Tavera-Cordero J. Nasal ala Alveolar Rhabdomyosarcoma in a pediatric patient. A rare case report. Acta otorrinolaringol cir cabeza cuello [Internet]. 2022Dec.30 [cited 2024Jul.3];50(4):300 - 33. Available from: https://revista.acorl.org.co/index.php/acorl/article/view/605
Section
Reportes de Casos
Author Biography

María Paula Olivera-Arenas, Universidad Nacional de Colombia

Residente Otorrinolaringologia Universidad Nacional de COlombia

References

Miettinen M. Small round cell tumor. In: Soft tissue tumors. Philadelphia: Churchill-Livingston; 2003. p. 427-62.

Bridge JA, Bowen JM, Smith RB. The small round blue cell tumors of the sinonasal area. Head Neck Pathol. 2010;4(1):84-93. doi: 10.1007/s12105-009-0158-6

Gnagi SH, Schraff SA. Nasal obstruction in newborns. Pediatr Clin North Am. 2013;60(4):903-22. doi: 10.1016/j.pcl.2013.04.007

Leboulanger N. Nasal obstruction in children. Eur Ann Otorhinolaryngol Head Neck Dis. 2016;133(3):183-6. doi: 10.1016/j.anorl.2015.09.011

Kinshucka AJ, Clark RW. Nasal masses in children. The Otorhinolaryngologist. 2012;5(3):133-38.

Chung SY, Unsal AA, Kilic S, Baredes S, Liu JK, Eloy JA. Pediatric sinonasal malignancies: A population-based analysis. Int J Pediatr Otorhinolaryngol. 2017;98:97-102. doi: 10.1016/j.

ijporl.2017.04.032

Tanyous GH. Rhabdomyosarcoma of the nasal vestibule in a child. Sultan Qaboos Univ Med J. 2006;6(2):87-9.

Hicks J, Flaitz C. Rhabdomyosarcoma of the head and neck in children. Oral Oncol. 2002;38(5):450-9. doi: 10.1016/s1368-8375(01)00105-1

Radzikowska J, Kukwa W, Kukwa A, Czarnecka A, Krzeski A. Rhabdomyosarcoma of the head and neck in children. Contemp Oncol (Pozn). 2015;19(2):98-107. doi: 10.5114/wo.2015.49158

Sung L, Anderson JR, Arndt C, Raney RB, Meyer WH, Pappo AS. Neurofibromatosis in children with Rhabdomyosarcoma: a report from the Intergroup Rhabdomyosarcoma study IV. J Pediatr. 2004;144(5):666-8. doi: 10.1016/j.jpeds.2004.02.026

Carnevale A, Lieberman E, Cárdenas R. Li-Fraumeni syndrome in pediatric patients with soft tissue sarcoma or osteosarcoma. Arch Med Res. 1997 Autumn;28(3):383-6

O’Neal JP, Ramdas J, Wood WE, Pellitteri PK. Parameningeal rhabdomyosarcoma in a patient with Costello syndrome. J Pediatr Hematol Oncol. 2004;26(6):389-92. doi:

1097/00043426-200406000-00012

Jung A, Bechthold S, Pfluger T, Renner C, Ehrt O. Orbital rhabdomyosarcoma in Noonan syndrome. J Pediatr Hematol Oncol. 2003;25(4):330-2. doi: 10.1097/00043426-200304000-

Smith AC, Squire JA, Thorner P, Zielenska M, Shuman C, Grant R, et al. Association of alveolar rhabdomyosarcoma with the Beckwith-Wiedemann syndrome. Pediatr Dev Pathol.

;4(6):550-8. doi: 10.1007/s10024001-0110-6

Arndt CA. Risk stratification of rhabdomyosarcoma: a moving target. Am Soc Clin Oncol Educ Book. 2013:415-9. doi: 10.14694/EdBook_AM.2013.33.415

Arndt CA, Stoner JA, Hawkins DS, Rodeberg DA, HayesJordan AA, Paidas CN, et al. Vincristine, actinomycin, and cyclophosphamide compared with vincristine, actinomycin, and

cyclophosphamide alternating with vincristine, topotecan, and cyclophosphamide for intermediate-risk rhabdomyosarcoma: children’s oncology group study D9803. J Clin Oncol.

;27(31):5182-8. doi: 10.1200/JCO.2009.22.3768

Oberlin O, Rey A, Lyden E, Bisogno G, Stevens MC, Meyer WH, et al. Prognostic factors in metastatic rhabdomyosarcomas: results of a pooled analysis from United States and European cooperative groups. J Clin Oncol. 2008;26(14):2384-9. doi: 10.1200/JCO.2007.14.7207

Parham DM, Barr FG. Alveolar rhabdomyosarcoma. In: Fletcher CDM, Unni KK, Mertens F, eds. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press; 2002. p. 150-52